PUBLICATIONS

Conjugated polymer of Multi-arm-PEG and dimethylsiloxane (CPMD) for the effective transdermal delivery of deoxycholic acid for fat reduction. Jeong H, Kim HL, Kim H, Lee MS, Cho JM, Park CL, Kim HI*, Park J*, Kim D*. Chem Eng J. 2025 Feb 1;505:159405. doi: 10.1016/j.cej.2025.159405

UG0712, A Ginsenoside Complex, Improved Endurance Performance and Changed Hepatic and Muscular Transcriptomic Signatures in C57BL/6N Male Mice. Yu SH, Oh HR, Park YH, Hong HR, Kim HJ, Park J, Han Y, Ko SG, Shin EC, Kim TG, Cho HT, Pan JH, Shim YY, Reaney MJT, Cho TJ, Hong JY, Kim YJ, Han BK, Lee GJ, Lee K, Do SG, Kim JK. J Med Food. 2025 Feb;28(2):127-143. doi: 10.1089/jmf.2024.k.0089. PMID: 39579161

The combination of water extracts of Curcumae Radix and Syzygii Flos improves benign prostatic hyperplasia by suppressing testosterone-induced proliferation of prostate cells in vivo and in vitro. Park JY, Park WY, Lee B, Song G, Jung Y, Kwak HJ, Ahn KS, Park J*, Um JY*. Nutr Res Pract. 2025 Jun;19(3):345-360. doi: 10.4162/nrp.2025.19.3.345. PMID: 40496052

Tetragonia tetragonioides extract prevented high-fat-diet-induced obesity and changed hepatic and adipose transcriptomic signatures in C57BL/6J male mice. Oh HR, Park YH, Hong HR, Kim HJ, Park J, Han Y, Ko SG, Shin EC, Kim TG, Cho HT, Pan JH, Shin HR, Shim YY, Reaney MJT, Cho TJ, Hong JY, Kim YJ, Han BK, Lee GJ, Lee K, Do SG, Kim JK. Biosci Biotechnol Biochem. 2025 Mar 24;89(4):599-611. doi: 10.1093/bbb/zbaf001. PMID: 39799382

Regulating Sirtuin 3-mediated mitochondrial dynamics through vanillic acid improves muscle atrophy in cancer-induced cachexia. Song G, Park J (co-1st), Jung Y, Park WY, Park JY, Jung SJ, Kim B, Choi M, Kim SH, Choe SK, Kwak HJ, Lee J, Lee KY, Ahn KS, Um JY. Commun Biol. 2025 Apr 9;8(1):585. doi: 10.1038/s42003-025-07770-0. PMID: 40204937

A Mixture of Nicotinamide Mononucleotide, Decursin, and l-Cysteine Lowered Senescence-Associated Markers In Vitro and Was Effective Against 2,4-Dinitrochlorobenzene-Induced Atopic Dermatitis In Vivo: An Application of Network Pharmacology. Shin HR, Choi Y, Bae SH, Kim TG, Cho HT, Cho TJ, Oh NS, Shim YY, Reaney MJT, Pan JH, Shin JO, Shin EC, Ko SG, Park J, Han Y, Choi KC, Kim YJ, Heo W, Lee K, Kim JK. J Med Food. 2025 May;28(5):490-500. doi: 10.1089/jmf.2024.k.0282. PMID: 40127227

Effects of mallotus furetianus extract on CYP3A activities in rats. Huang W, Kim HI, Cao F, Li S, Park J*, Li P*. Sci Rep. 2025 May 27;15(1):18530. doi: 10.1038/s41598-025-02193-7. PMID: 40425598

Transdermal therapeutic polymer: in situ synthesis of biocompatible polymer using 5-aminolevulinic acid as a photosensitizer precursor and a polymer initiator. Kim J, Seo EW, Choi H, Kim HI, Park J, Jung J, Kim D. Mater Horiz. 2025 Jun 3;12(11):3878-3887. doi: 10.1039/d5mh00099h. PMID: 40071813

The combination of water extracts of Curcumae Radix and Syzygii Flos improves benign prostatic hyperplasia by suppressing testosterone-induced proliferation of prostate cells in vivo and in vitro. Park JY, Park WY, Lee B, Song G, Jung Y, Kwak HJ, Ahn KS, Park J*, Um JY*. Nutr Res Pract. 2025 Jun;19(3):345-360. doi: 10.4162/nrp.2025.19.3.345. PMID: 40496052

Integrating Network Pharmacology and Optimization of Preparation Methods to Enhance the Anticancer Effect of Cordyceps militaris on Lung Cancer. Kim HL, Park J, Kim HI, Boo M, Sim JH, Kim H, Choi H, An S, Yang H, Shin S, Han Y, Kim H, Park J*, Lee K*. Anticancer Res. 2025 Jul;45(7):2963-2984. doi: 10.21873/anticanres.17663. PMID: 40578945

In vivo exosome imaging: applications of diverse visualization techniques. Hong S, Jo HC, Kim HL, Kim H, Lee J, Jeon J, Rhim J, Rhee S, Park J, Chung YH, Jung KO. BMB Rep. 2025 Aug;58(8):340-349. doi: 10.5483/BMBRep.2025-0060. PMID: 40754774

AMP-Activated Protein Kinases in Health and Disease. Kim HI, Han Y*, Park J*. Int J Mol Sci. Int J Mol Sci. 2025 Aug 21;26(16):8075. doi: 10.3390/ijms26168075. PMID: 40869395

Modified Saengmaeksan, an herbal formula containing six herbs, improves hypertension through RhoA/Rho kinase-mediated vasorelaxation. Seok YM, Kim HL, Kim HI, Moon H, Han Y, Cho ES, Leem HH, Kim HJ, Shin S, Kim SJ, Jung JK, Huang W, Jung KO, Lee DS, Jin SG, Kim H, Yang C, Lee K*, Park J*. Integr Med Res. 2025 Dec;14(4):101207. doi: 10.1016/j.imr.2025.101207. PMID: 40896355

Programmed Aggregation of Lipidated Nitrobenzoselenadiazole as a Photo-Activatable Pyroptosis Inducer. An JM, Choi H, Kim HI*, Kim DY, Kim J, Park J, Jung J*, Jeong NY*, Kim D*. Adv Healthc Mater. 2025 Sep;14(24):e01567. doi: 10.1002/adhm.202501567. PMID: 40760986

Traumatic Liver Injury Increases Susceptibility to Bacterial Pneumonia in Swine. Kim HI, Seshadri A, Harbison J, Csizmadia E, Park J, Gallo D, Voltarelli VA, Scheiflinger A, Kirby JE, Hauser CJ, Otterbein LE*. J Trauma Acute Care Surg. J Trauma Acute Care Surg. 2025 Aug 28. doi: 10.1097/TA.0000000000004768. Online ahead of print. PMID: 40875191.

Herbal Combination of Angelica gigas, Zingiber officinale, and Aconitum carmichaeli Alleviates High Fat Diet-Induced Non-Alcoholic Fatty Liver Disease in Mice Through NRF2-Mediated Regulation of Adipogenesis and Non-Shivering Thermogenesis. Kim H, Kim HL, Boo M, Choi H, Han J, Nam S, Kang SJ, Kim JK, Han Y, Jung JH, Kim W, Kim KI, Um JY, Park J*, Otterbein LE*, Kim HI*, Ko SG*. Food Sci Nutr. 2025 Nov 25;13(12):e71199. doi: 10.1002/fsn3.71199. PMID: 41306340

Inhibition of MID1IP1 induces ferroptosis and suppresses c-Myc expression in colorectal cancer cell. Oh JJ, Lee YJ, Han YJ, Sasaki Y, Park J, Kim W, Jung JH. Genes Genomics. 2025 Dec 4. doi: 10.1007/s13258-025-01717-9. Online ahead of print. PMID: 41343117

Moderating AKT signaling with baicalein protects against weight loss by preventing muscle atrophy in a cachexia model caused by CT26 colon cancer. Song G, Park WY, Jiao W, Park JY, Jung SJ, Ma S, Lee J, Lee KY, Choe SK, Park J, Kwak HJ, Ahn KS, Um JY. Biochim Biophys Acta Mol Cell Res. 2024 Mar;1871(3):119670. doi: 10.1016/j.bbamcr.2024.119670. PMID: 38220095

Recent advances in extracellular vesicles for therapeutic cargo delivery. Kim HI, Park J (co-1st), Zhu Y, Wang X, Han Y, Zhang D. Exp Mol Med. 2024 Apr;56(4):836-849. doi: 10.1038/s12276-024-01201-6. PMID: 38556545

Bee venom acupuncture and herbal medicine for hand eczema: Two case reports and an in vivo study. Jang S, Kim HI, Jung JW, Boo M, Sung SH, Park J*, Kim S*. Explore (NY). 2024 Sep-Oct;20(5):102994. doi: 10.1016/j.explore.2024.03.002. PMID: 38637265

Epigallocatechin gallate protects against fat and muscle atrophy in B16BL6 melanoma-bearing mice on a high-fat diet. Park WY, Song G, Park JY, Jung SJ, Kim S, Ahn KS, Choe SK, Kwak HJ, Park J, Um JY. Life Sci. 2024 Jul 1;348:122677. doi: 10.1016/j.lfs.2024.122677. PMID: 38702026

The role of immune cells in different stages of atherosclerosis. He C, Kim HI, Park J*, Guo J*, Huang W*. Int J Med Sci. 2024 Apr 22;21(6):1129-1143. doi: 10.7150/ijms.94570. PMID: 38774746

Inhibiting AGS Cancer Cell Proliferation through the Combined Application of Aucklandiae Radix and Hyperthermia: Investigating the Roles of Heat Shock Proteins and Reactive Oxygen Species. Ahn CR, Ha IJ, Kim JE, Ahn KS, Park J*, Baek SH. Antioxidants (Basel). 2024 May 3;13(5):564. doi: 10.3390/antiox13050564. PMID: 38790669

The multi-herbal decoction SH003 alleviates LPS-induced acute lung injury by targeting inflammasome and extracellular traps in neutrophils. Kim HI, Han Y, Kim MH, Boo M, Cho KJ, Kim HL, Lee IS, Jung JH, Kim W, Um JY, Park J*, Ko SG*. Phytomedicine. 2024 Oct;133:155926. doi: 10.1016/j.phymed.2024.155926. PMID: 39128302

Momoridica charantia and fermented Momoridica charantia with Leuconostoc mesenteroides MKSR change intestinal microbial diversity indices and compositions in high-fat and high-cholesterol diet-fed C57BL/6 male mice. Moon H, Lee K, Ha JH, Kim NY, Shin HR, Cho TJ, Oh NS, Park J, Tang J, Kim JK, Kim M. Front Vet Sci. 2024 Dec 17;11:1496067. doi: 10.3389/fvets.2024.1496067. eCollection 2024. PMID: 39742315

Panax ginseng C.A. meyer alleviates benign prostatic hyperplasia while preventing finasteride-induced side effects. Park JY, Park WY, Song G, Jung SJ, Kim B, Choi M, Kim SH, Park J, Kwak HJ, Ahn KS, Lee JH, Um JY. Front Pharmacol. 2023 Jan 12;14:1039622. doi: 10.3389/fphar.2023.1039622. PMID: 36713838

Ponciri Fructus Immatarus Sensitizes the Apoptotic Effect of Hyperthermia Treatment in AGS Gastric Cancer Cells through ROS-Dependent HSP Suppression. Ahn CR, Kim HI, Kim JE, Ha IJ, Ahn KS, Park J, Kim YW, Baek SH. Biomedicines. 2023 Jan 30;11(2):405. doi: 10.3390/biomedicines11020405. PMID: 36830941

DANGER Signals Activate G-Protein Receptor Kinases Suppressing Neutrophil Function and Predisposing to Infection After Tissue Trauma. Kim HI, Park J (co-1st), Gallo D, Shankar S, Konecna B, Han Y, Banner-Goodspeed V, Capers KR, Ko SG, Otterbein LE, Itagaki K, Hauser CJ. Ann Surg. 2023 Dec 1;278(6):e1277-e1288. doi: 10.1097/SLA.0000000000005898. PMID: 37154066

The Role of Natural Products in the Improvement of Cancer-Associated Cachexia. Han Y, Kim HI, Park J*. Int J Mol Sci. 2023 May 15;24(10):8772. doi: 10.3390/ijms24108772. PMID: 37240117

Antidiabetic Effect of Fermented Mesembryanthemum crystallinum L. in db/db Mice Involves Regulation of PI3K-Akt Pathway. Kim HL, Jung Y, Kim HI, Sung NY, Kim MJ, Han IJ, Kim G, Nho EY, Park SY, Han Y, Jung JH, Kim DS, Park J*. Curr Issues Mol Biol. 2023 Aug 3;45(8):6415-6431. doi: 10.3390/cimb45080405. PMID: 37623224

Natural Antioxidants in Obesity and Related Diseases. Kim HI, Park J*. Antioxidants (Basel). 2023 Nov 5;12(11):1966. doi: 10.3390/antiox12111966. PMID: 38001819

PEX13 is required for thermogenesis of white adipose tissue in cold-exposed mice. Park WY, Park J (co-1st), Lee S, Song G, Nam IK, Ahn KS, Choe SK, Um JY. Biochim Biophys Acta Mol Cell Biol Lipids. 2022 Jan;1867(1):159046. doi: 10.1016/j.bbalip.2021.159046. PMID: 34517131

Plasma and wound fluids from trauma patients suppress neutrophil extracellular respiratory burst. Kim HI, Park J (co-1st), Konecna B, Huang W, Riça I, Gallo D, Otterbein LE, Itagaki K, Hauser CJ. J Trauma Acute Care Surg. 2022 Feb 1;92(2):330-338. doi: 10.1097/TA.0000000000003461. PMID: 34789698

Comprehensive traditional East Asian medicine treatment strategy for obesity considering the therapeutic effects and adverse events: A protocol for systematic review and network meta-analysis. Chu H, Kang B, Youn BY, Kim KI, Park J, Leem J. Medicine. 2022 Feb 11;101(6):e28673. doi: 10.1097/MD.0000000000028673. PMID: 35147089

Hyperthermia Treatment as a Promising Anti-Cancer Strategy: Therapeutic Targets, Perspective Mechanisms and Synergistic Combinations in Experimental Approaches. Yi GY, Kim MJ, Kim HI, Park J*, Baek SH. Antioxidants. 2022 Mar 24;11(4):625. doi: 10.3390/antiox11040625. PMID: 35453310

Chaenomeles Fructus (CF), the Fruit of Chaenomeles sinensis Alleviates IL-1β Induced Cartilage Degradation in Rat Articular Chondrocytes. Yeo C, Ahn CR, Kim JE, Kim YW, Park J, Ahn KS, Ha IJ, Lee YJ, Baek SH, Ha IH. Int J Mol Sci. 2022 Apr 14;23(8):4360. doi: 10.3390/ijms23084360. PMID: 35457176

Ellagic acid improves benign prostate hyperplasia by regulating androgen signaling and STAT3. Park WY, Song G, Park JY, Ahn KS, Kwak HJ, Park J, Lee JH, Um JY. Cell Death Dis. 2022 Jun 17;13(6):554. doi: 10.1038/s41419-022-04995-3. PMID: 35715415

Therapeutic role of Glycyrrhiza Uralensis fisher on benign prostatic hyperplasia through 5 alpha reductase regulation and apoptosis. Park JY, Park WY, Park J, Ahn KS, Lee JH, Kwak HJ, Um JY. Phytomedicine. 2022 Oct;105:154371. doi: 10.1016/j.phymed.2022.154371. PMID: 35964456

Immune-Enhancing Effect of Sargassum horneri on Cyclophosphamide-Induced Immunosuppression in BALB/c Mice and Primary Cultured Splenocytes. Kim HI, Kim DS, Jung Y, Sung NY, Kim M, Han IJ, Nho EY, Hong JH, Lee JK, Boo M, Kim HL, Baik S, Jung KO, Lee S, Kim CS, Park J*. Molecules. 2022 Nov 26;27(23):8253. doi: 10.3390/molecules27238253. PMID: 36500343

Anmyungambi Decoction Ameliorates Obesity through Activation of Non-Shivering Thermogenesis in Brown and White Adipose Tissues. Park WY, Song G, Boo M, Kim HI, Park JY, Jung SJ, Choi M, Kim B, Kim YD, Kim MH, Kim KI, Kwak HJ, Leem J, Um JY, Park J*. Antioxidants. 2022 Dec 26;12(1):49. doi: 10.3390/antiox12010049. PMID: 36670911

Monocyte exocytosis of mitochondrial danger-associated molecular patterns in sepsis suppresses neutrophil chemotaxis. Konecna B, Park J, Kwon WY, Vlkova B, Zhang Q, Huang W, Kim HI, Yaffe MB, Otterbein LE, Itagaki K, Hauser CJ. J Trauma Acute Care Surg. 2021 Jan 1;90(1):46-53. doi: 10.1097/TA.0000000000002973. PMID: 33021603

Farnesol induces mitochondrial/peroxisomal biogenesis and thermogenesis by enhancing the AMPK signaling pathway in vivo and in vitro. Cho SY, Lim S, Ahn KS, Kwak HJ, Park J*, Um JY*. Pharmacol Res. 2021 Jan;163:105312. doi: 10.1016/j.phrs.2020.105312. PMID: 33246168

Ellagic acid induces beige remodeling of white adipose tissue by controlling mitochondrial dynamics and SIRT3. Park WY, Park J, Ahn KS, Kwak HJ, Um JY. FASEB J. 2021 Jun;35(6):e21548. doi: 10.1096/fj.202002491R. PMID: 33956354

Direct Airway Instillation of Neutrophils Overcomes Chemotactic Deficits Induced by Injury. Zhang Q, Kwon WY, Vlková B, Riça I, Kaczmarek E, Park J, Kim HI, Konecna B, Jung F, Douglas G, Otterbein LE, Hauser CJ, Itagaki K. Shock. 2021 Jul 1;56(1):119-124. doi: 10.1097/SHK.0000000000001691. PMID: 33181622

Fruit of Gardenia jasminoides Induces Mitochondrial Activation and Non-Shivering Thermogenesis through Regulation of PPARγ. Park WY, Song G, Park JY, Kim KI, Ahn KS, Kwak HJ, Leem J, Um JY, Park J. Antioxidants. 2021 Sep 5;10(9):1418. doi: 10.3390/antiox10091418. PMID: 34573050

Role of Mitochondria-Derived Danger Signals Released After Injury in Systemic Inflammation and Sepsis. Itagaki K, Riça I, Konecna B, Kim HI, Park J, Kaczmarek E, Hauser CJ. Antioxid Redox Signal. 2021 Nov 20;35(15):1273-1290. doi: 10.1089/ars.2021.0052. PMID: 33847158

Raphani Semen (Raphanus sativus L.) Ameliorates Alcoholic Fatty Liver Disease by Regulating De Novo Lipogenesis. Park WY, Song G, Noh JH, Kim T, Kim JJ, Hong S, Park J, Um JY. Nutrients. 2021 Dec 13;13(12):4448. doi: 10.3390/nu13124448. PMID: 34959999

Gomisin A ameliorates metastatic melanoma by inhibiting AMPK and ERK/JNK-mediated cell survival and metastatic phenotypes. Han YH, Mun JG, Jeon HD, Park J, Kee JY, Hong SH. Phytomedicine. 2020 Mar;68:153147. doi: 10.1016/j.phymed.2019.153147. PMID: 32028184

Anti-Anaphylactic Activity of Isoquercitrin (Quercetin-3-O-β-d-Glucose) in the Cardiovascular System of Animals. Park J*. Biomedicines. 2020 May 29;8(6):139. doi: 10.3390/biomedicines8060139. PMID: 32486018

Ephedrae Herba in combination with herbal medicine (Zhizichi decoction and Phellodendri Cortex) for weight reduction: a case series. Lee E, Yoon SH, Kim H, Kim YD, Leem J, Park J. Integr Med Res. 2020 Jun;9(2):100408. doi: 10.1016/j.imr.2020.100408. PMID: 32405455

Fruit of Hovenia dulcis Thunb. Induces Nonshivering Thermogenesis through Mitochondrial Biogenesis and Activation by SIRT1 in High-Fat Diet-Fed Obese Mice and Primary Cultured Brown Adipocytes. Song G, Kim HL, Jung Y, Park J, Lee JH, Ahn KS, Kwak HJ, Um JY. J Agric Food Chem. 2020 Jun 17;68(24):6715-6725. doi: 10.1021/acs.jafc.0c01117. PMID: 32450691

Vanillic Acid Improves Comorbidity of Cancer and Obesity through STAT3 Regulation in High-Fat-Diet-Induced Obese and B16BL6 Melanoma-Injected Mice. Park J, Cho SY, Kang J, Park WY, Lee S, Jung Y, Kang MW, Kwak HJ, Um JY. Biomolecules. 2020 Jul 24;10(8):1098. doi: 10.3390/biom10081098. PMID: 32722030

A phytoestrogen secoisolariciresinol diglucoside induces browning of white adipose tissue and activates non-shivering thermogenesis through AMPK pathway. Kang J, Park J (co-1st), Park WY, Jiao W, Lee S, Jung Y, Youn DH, Song G, Cho SY, Kim WY, Park JY, Ahn KS, Kwak HJ, Um JY. Pharmacol Res. 2020 Aug;158:104852. doi: 10.1016/j.phrs.2020.104852. PMID: 32438038

Combination Therapy with Cinnamaldehyde and Hyperthermia Induces Apoptosis of A549 Non-Small Cell Lung Carcinoma Cells via Regulation of Reactive Oxygen Species and Mitogen-Activated Protein Kinase Family. Park J, Baek SH. Int J Mol Sci. 2020 Aug 28;21(17):6229. doi: 10.3390/ijms21176229. PMID: 32872198

Cinnamaldehyde and Hyperthermia Co-Treatment Synergistically Induces ROS-Mediated Apoptosis in ACHN Renal Cell Carcinoma Cells. Ahn CR, Park J (co-1st), Kim JE, Ahn KS, Kim YW, Jeong M, Kim HJ, Park SH, Baek SH. Biomedicines. 2020 Sep 17;8(9):357. doi: 10.3390/biomedicines8090357. PMID: 32957430

Platycodin D, a novel activator of AMP-activated protein kinase, attenuates obesity in db/db mice via regulation of adipogenesis and thermogenesis. Kim HL, Park JJ, Jung Y, Ahn KS, Um JY. Phytomedicine. 2019 Jan;52:254-263. doi: 10.1016/j.phymed.2018.09.227. PMID: 30599906

β-Lapachone Regulates Obesity through Modulating Thermogenesis in Brown Adipose Tissue and Adipocytes: Role of AMPK Signaling Pathway. Kwak HJ, Jeong MY, Um JY, Park J. Am J Chin Med. 2019;47(4):803-822. doi: 10.1142/S0192415X19500423. PMID: 31094212

Aconiti Lateralis Radix Preparata, the Dried Root of Aconitum carmichaelii Debx., Improves Benign Prostatic Hyperplasia via Suppressing 5-Alpha Reductase and Inducing Prostate Cell Apoptosis. Park J, Youn DH, Um JY. Evid Based Complement Alternat Med. 2019 Jul 31;2019:6369132. doi: 10.1155/2019/6369132. PMID: 31467577

Bitter Orange (Citrus aurantium Linné) Improves Obesity by Regulating Adipogenesis and Thermogenesis through AMPK Activation. Park J, Kim HL, Jung Y, Ahn KS, Kwak HJ, Um JY. Nutrients. 2019 Aug 22;11(9):1988. doi: 10.3390/nu11091988. PMID: 31443565

Rubrofusarin-6-β-gentiobioside inhibits lipid accumulation and weight gain by regulating AMPK/mTOR signaling. Han YH, Kee JY, Park SH, Mun JG, Jeon HD, Park J, Zou QP, Liu XQ, Hong SH. Phytomedicine. 2019 Sep;62:152952. doi: 10.1016/j.phymed.2019.152952. PMID: 31132754 

Black Raspberry (Rubus coreanus Miquel) Promotes Browning of Preadipocytes and Inguinal White Adipose Tissue in Cold-Induced Mice. Park WY, Choe SK, Park J*, Um J*. Nutrients. 2019 Sep 10;11(9):2164. doi: 10.3390/nu11092164. PMID: 31509935

Zileuton, a 5-Lipoxygenase Inhibitor, Exerts Anti-Angiogenic Effect by Inducing Apoptosis of HUVEC via BK Channel Activation. Lim HJ, Park J (co-1st), Um JY, Lee SS, Kwak HJ. Cells. 2019 Sep 30;8(10):1182. doi: 10.3390/cells8101182. PMID: 31575085

Ginsenoside Rb1 Induces Beta 3 Adrenergic Receptor-Dependent Lipolysis and Thermogenesis in 3T3-L1 Adipocytes and db/db Mice. Lim S, Park J (co-1st), Um JY. Front Pharmacol. 2019 Oct 15;10:1154. doi: 10.3389/fphar.2019.01154. PMID: 31680950

Taeumjowi-tang, a Traditional Korean Sasang Remedy, Improves Obesity-Atopic Dermatitis Comorbidity by Regulating Hypoxia-Inducible Factor 1 Alpha. Park J, Youn DH, Kang J, Ahn KS, Kwak HJ, Um JY. Front Pharmacol. 2019 Dec 20;10:1458. doi: 10.3389/fphar.2019.01458. PMID: 31920651

Secoisolariciresinol diglucoside inhibits adipogenesis through the AMPK pathway. Kang J, Park J, Kim HL, Jung Y, Youn DH, Lim S, Song G, Park H, Jin JS, Kwak HJ, Um JY. Eur J Pharmacol. 2018 Feb 5;820:235-244. doi: 10.1016/j.ejphar.2017.12.038. PMID: 29269018

Vanillic acid attenuates obesity via activation of the AMPK pathway and thermogenic factors in vivo and in vitro. Jung Y, Park J, Kim HL, Sim JE, Youn DH, Kang J, Lim S, Jeong MY, Yang WM, Lee SG, Ahn KS, Um JY. FASEB J. 2018 Mar;32(3):1388-1402. doi: 10.1096/fj.201700231RR. PMID: 29141998

Berberine Improves Benign Prostatic Hyperplasia via Suppression of 5 Alpha Reductase and Extracellular Signal-Regulated Kinase in Vivo and in Vitro. Youn DH, Park J, Kim HL, Jung Y, Kang J, Lim S, Song G, Kwak HJ, Um JY. Front Pharmacol. 2018 Jul 16;9:773. doi: 10.3389/fphar.2018.00773. PMID: 30061836

Synergistic Effect of Bupleuri Radix and Scutellariae Radix on Adipogenesis and AMP-Activated Protein Kinase: A Network Pharmacological Approach. Lee J, Park J (co-1st), Park H, Youn DH, Lee J, Hong S, Um JY. Evid Based Complement Alternat Med. 2018 Aug 23;2018:5269731. doi: 10.1155/2018/5269731. PMID: 30210572

Eclipta prostrata Improves DSS-Induced Colitis through Regulation of Inflammatory Response in Intestinal Epithelial Cells. Kim DS, Kim SH, Kee JY, Han YH, Park J, Mun JG, Joo MJ, Jeon YD, Kim SJ, Park SH, Park SJ, Um JY, Hong SH. Am J Chin Med. 2017;45(5):1047-1060. doi: 10.1142/S0192415X17500562. PMID: 28659027

Chrysophanic acid reduces testosterone-induced benign prostatic hyperplasia in rats by suppressing 5α-reductase and extracellular signal-regulated kinase. Youn DH, Park J (co-1st), Kim HL, Jung Y, Kang J, Jeong MY, Sethi G, Seok Ahn K, Um JY. Oncotarget. 2017 Feb 7;8(6):9500-9512. doi: 10.18632/oncotarget.13430. PMID: 27880726

Korean Red Ginseng improves atopic dermatitis-like skin lesions by suppressing expression of proinflammatory cytokines and chemokines in vivo and in vitro. Kee JY, Jeon YD, Kim DS, Han YH, Park J, Youn DH, Kim SJ, Ahn KS, Um JY, Hong SH. J Ginseng Res. 2017 Apr;41(2):134-143. doi: 10.1016/j.jgr.2016.02.003. PMID: 28413317

Albiflorin ameliorates obesity by inducing thermogenic genes via AMPK and PI3K/AKT in vivo and in vitro. Jeong MY, Park J, Youn DH, Jung Y, Kang J, Lim S, Kang MW, Kim HL, So HS, Park R, Hong SH, Um JY. Metabolism. 2017 Aug;73:85-99. doi: 10.1016/j.metabol.2017.05.009. PMID: 28732574

Farnesol Has an Anti-obesity Effect in High-Fat Diet-Induced Obese Mice and Induces the Development of Beige Adipocytes in Human Adipose Tissue Derived-Mesenchymal Stem Cells. Kim HL, Jung Y, Park J, Youn DH, Kang J, Lim S, Lee BS, Jeong MY, Choe SK, Park R, Ahn KS, Um JY. Front Pharmacol. 2017 Sep 20;8:654. doi: 10.3389/fphar.2017.00654. PMID: 29033835

Vanillic acid attenuates testosterone-induced benign prostatic hyperplasia in rats and inhibits proliferation of prostatic epithelial cells. Jung Y, Park J (co-1st), Kim HL, Youn DH, Kang J, Lim S, Jeong MY, Sethi G, Park SJ, Ahn KS, Um JY. Oncotarget. 2017 Aug 3;8(50):87194-87208. doi: 10.18632/oncotarget.19909. PMID: 29152074

β-Lapachone Inhibits Lung Metastasis of Colorectal Cancer by Inducing Apoptosis of CT26 Cells. Kee JY, Han YH, Park J, Kim DS, Mun JG, Ahn KS, Kim HJ, Um JY, Hong SH. Integr Cancer Ther. 2017 Dec;16(4):585-596. doi: 10.1177/1534735416681638. PMID: 27923905

Lipin1-Mediated Repression of Adipogenesis by Rutin. Han YH, Kee JY, Park J, Kim DS, Shin S, Youn DH, Kang J, Jung Y, Lee YM, Park JH, Kim SJ, Um JY, Hong SH. Am J Chin Med. 2016;44(3):565-78. doi: 10.1142/S0192415X16500312. PMID: 27109161

Veratri Nigri Rhizoma et Radix (Veratrum nigrum L.) and Its Constituent Jervine Prevent Adipogenesis via Activation of the LKB1-AMPKα-ACC Axis In Vivo and In Vitro. Park J, Jeon YD, Kim HL, Kim DS, Han YH, Jung Y, Youn DH, Kang J, Yoon D, Jeong MY, Lee JH, Hong SH, Lee J, Um JY. Evid Based Complement Alternat Med. 2016;2016:8674397. doi: 10.1155/2016/8674397. PMID: 27143989

Cinnamomi Cortex (Cinnamomum verum) Suppresses Testosterone-induced Benign Prostatic Hyperplasia by Regulating 5α-reductase. Choi HM, Jung Y, Park J (co 1st), Kim HL, Youn DH, Kang J, Jeong MY, Lee JH, Yang WM, Lee SG, Ahn KS, Um JY. Sci Rep. 2016 Aug 23;6:31906. doi: 10.1038/srep31906. PMID: 27549514

Arctigenin Inhibits Adipogenesis by Inducing AMPK Activation and Reduces Weight Gain in High-Fat Diet-Induced Obese Mice. Han YH, Kee JY, Park J, Kim HL, Jeong MY, Kim DS, Jeon YD, Jung Y, Youn DH, Kang J, So HS, Park R, Lee JH, Shin S, Kim SJ, Um JY, Hong SH. J Cell Biochem. 2016 Sep;117(9):2067-77. doi: 10.1002/jcb.25509. PMID: 26852013

Inhibitory effect of quercetin on colorectal lung metastasis through inducing apoptosis, and suppression of metastatic ability. Kee JY, Han YH, Kim DS, Mun JG, Park J, Jeong MY, Um JY, Hong SH. Phytomedicine. 2016 Dec 1;23(13):1680-1690. doi: 10.1016/j.phymed.2016.09.011. PMID: 27823633

Anti-obesity effects of Arctii Fructus (Arctium lappa) in white/brown adipocytes and high-fat diet-induced obese mice. Han YH, Kee JY, Kim DS, Park J, Jeong MY, Mun JG, Park SJ, Lee JH, Um JY, Hong SH. Food Funct. 2016 Dec 7;7(12):5025-5033. doi: 10.1039/c6fo01170e. PMID: 27882370

Chrysophanic Acid Suppresses Adipogenesis and Induces Thermogenesis by Activating AMP-Activated Protein Kinase Alpha In vivo and In vitro. Lim H, Park J (co-1st), Kim HL, Kang J, Jeong MY, Youn DH, Jung Y, Kim YI, Kim HJ, Ahn KS, Kim SJ, Choe SK, Hong SH, Um JY. Front Pharmacol. 2016 Dec 8;7:476. doi: 10.3389/fphar.2016.00476. PMID: 28008317

Beneficial effects of the traditional medicine Igongsan and its constituent ergosterol on dextran sulfate sodium-induced colitis in mice. Kim SJ, Shin HJ, Lee GH, Kim DS, Kim HL, Park J, Jung Y, Youn DH, Kang J, Hong SH, Um JY. Mol Med Rep. 2015 Sep;12(3):3549-3556. doi: 10.3892/mmr.2015.3824. PMID: 26005209

Platycodon grandiflorum A. De Candolle Ethanolic Extract Inhibits Adipogenic Regulators in 3T3-L1 Cells and Induces Mitochondrial Biogenesis in Primary Brown Preadipocytes. Kim HL, Park J, Park H, Jung Y, Youn DH, Kang J, Jeong MY, Um JY. J Agric Food Chem. 2015 Sep 9;63(35):7721-30. doi: 10.1021/acs.jafc.5b01908. PMID: 26244589

The antiinflammatory mechanism of Igongsan in mouse peritoneal macrophages via suppression of NF-κB/Caspase-1 activation. Kim SJ, Shin HJ, Lee BJ, Kim DS, Lee JH, Jeong MY, Kim HL, Park J, Lim H, Kim SH, Hong SH, Hwang MW, Um JY. Phytother Res. 2014 May;28(5):736-44. doi: 10.1002/ptr.5058. PMID: 23956075

The AMPK pathway mediates an anti-adipogenic effect of fruits of Hovenia dulcis Thunb. Kim HL, Sim JE, Choi HM, Choi IY, Jeong MY, Park J, Jung Y, Youn DH, Cho JH, Kim JH, Hwang MW, Jin JS, Hong SH, Cho HW, Um JY. Food Funct. 2014 Nov;5(11):2961-8. doi: 10.1039/c4fo00470a. PMID: 25224378

Interaction of Veratrum nigrum with Panax ginseng against Obesity: A Sang-ban Relationship. Park J, Jeon YD, Kim HL, Lim H, Jung Y, Youn DH, Jeong MY, Kim HJ, Kim SH, Kim SJ, Hong SH, Um JY. Evid Based Complement Alternat Med. 2013;2013:732126. doi: 10.1155/2013/732126. PMID: 24073007

Corni Fructus Containing Formulation Attenuates Weight Gain in Mice with Diet-Induced Obesity and Regulates Adipogenesis through AMPK. Kim HL, Jeon YD, Park J, Rim HK, Jeong MY, Lim H, Ko SG, Jang HJ, Lee BC, Lee KT, Lee KM, Lee H, Kim SH, Kim SJ, Hong SH, Um JY. Evid Based Complement Alternat Med. 2013;2013:423741. doi: 10.1155/2013/423741. PMID: 24171041

Rubi Fructus (Rubus coreanus) Inhibits Differentiation to Adipocytes in 3T3-L1 Cells. Jeong MY, Kim HL, Park J, An HJ, Kim SH, Kim SJ, So HS, Park R, Um JY, Hong SH. Evid Based Complement Alternat Med. 2013;2013:475386. doi: 10.1155/2013/475386. PMID: 24288561

Proinflammatory cytokine IL-1 β polymorphisms in sudden sensorineural hearing loss. Um JY, Jang CH, Kim HL, Cho YB, Park J, Lee SJ, Kim YB, Kim HJ, Ahn KS, Jang HJ, Lee SG, Lee H, Lee KM, Kim SJ, Hong SH. Immunopharmacol Immunotoxicol. 2013 Feb;35(1):52-6. doi: 10.3109/08923973.2012.719523. PMID: 23013363

Saengmaeksan inhibits inflammatory mediators by suppressing RIP-2/caspase-1 activation. Jeong MY, Park DH, Kim MC, Park J, Kim DS, Jeon YD, Kim SJ, Ahn KS, Kim SH, Lee JH, Jung HJ, Hong SH, Um JY. Immunopharmacol Immunotoxicol. 2013 Apr;35(2):241-50. doi: 10.3109/08923973.2012.757617. PMID: 23356698

Eucommiae cortex inhibits TNF-α and IL-6 through the suppression of caspase-1 in lipopolysaccharide-stimulated mouse peritoneal macrophages. Kim MC, Kim DS, Kim SJ, Park J, Kim HL, Kim SY, Ahn KS, Jang HJ, Lee SG, Lee KM, Hong SH, Um JY. Am J Chin Med. 2012;40(1):135-49. doi: 10.1142/S0192415X12500115. PMID: 22298454